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When formulating its recommendations for the Trustees, the Research Committee particularly favours activities that seem likely to lead to improved systems of managing land, water, plants and animals in ways which will enhance the productivity and quality of food, fisheries, plants and forests, while simultaneously conserving the natural environment, preserving biodiversity, avoiding pollution of soils and water, and enhancing human welfare. In assessing applications for new projects, scientific merit is of paramount importance.

As at January 2012, the Australia & Pacific Science Foundation had funded 54 completed projects with grants totalling $1,342,004.

As at January 2012, the Pacific Biological Foundation had funded 21 completed projects with grants totalling $551,661.

27 current projects are presently being funded by the Australia & Pacific Science Foundation with grants totalling $859,963.

The endangered Sandhill Dunnart is under threat by mining exploration in its semi-arid habitat. This project, supported by the APSF, will use a combination of ecological and genetic information to assist in developing an effective management plan for the species.